Lipoprotein lipase as a therapeutic target for dyslipidemia.
نویسندگان
چکیده
The importance of lipoprotein lipase (LPL) in the regulation of overall lipid metabolism in humans and other animals is well documented. The major goal of this review is to identify and justify features that make LPL an important drug target for lipid management in particular for triglyceride lowering and HDL elevation, and propose strategies to modulate LPL activity.
منابع مشابه
Association between Lipoprotein Lipase Hind III Polymorphism and Serum Levels of Lipids in Semnan City
Background & Aims: Lipoprotein lipase (LPL) is one of the key enzymes regulating the metabolism of triglycerides (TG) and HDL cholesterol. The lipoprotein lipase (LPL) gene polymorphisms are possibly involved in the pathophysiology of dyslipidemia. Hind III polymorphism is one of the most common polymorphisms in LPL gene. In some studies, association of Hind III polymorphism with dyslipidemia h...
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عنوان ژورنال:
- Frontiers in bioscience : a journal and virtual library
دوره 8 شماره
صفحات -
تاریخ انتشار 2003